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It is a 3-in-1 reference e-book. It offers an entire clinical dictionary overlaying 1000's of phrases and expressions with regards to bipolar disease. It additionally offers vast lists of bibliographic citations. ultimately, it presents details to clients on tips to
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Extra info for Bipolar Disorder - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References
Patients with bipolar disorder will be scanned on three occasions at weeks 2,6, and 10 of this study. Mood at time of each scan will be assessed using the Young Mania Rating Scale and the Hamilton Depression Rating Scale. A priori regions of interest for this study will include the bilateral caudate nuclei and the anterior cingulate cortex, as pilot studies suggest that these brain regions demonstrate mood state, medication, and diagnosis dependent alteration in choline and myo-inositol resonance intensities.
Aravinda Chakravarti, Terri Beaty, Jonathan Pevsner, and Forrest Spencer will provide expert consultation in bioinformatics, LD and microarray analysis. Dr. Francis McMahon, Chief, Genetic Basis of Mood and Anxiety Disorders, NIMH, will provide facilities and assistance in SNP genotyping technology. The didactic training will be complemented by the proposed research project, which is designed to test the hypothesis that gene variations underlie susceptibility to bipolar disorder. This hypothesis has been supported through twin, adoption, and family studies and by recent reports of linkage to a number of regions in the human genome.
Over the course of the study, patients will be assessed for changes in psychopathology, mood symptoms, suicidal behavior, aggressive behavior and substance abuse. They predict that subjects on lithium will have less suicidal behavior, including completion, attempt or hospitalization for suicidal ideation than subjects on valproate and that this effect will be independent of mood stabilization. The project will test the following hypotheses: (1) Lithium treatment will be superior to valproate in the prevention of suicidal behavior (suicidal acts or episodes of suicidal ideation with a plan that would require a change in treatment such as addition of a rescue medication or hospitalization).