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Additional resources for Chemotherapy Regimens and Cancer Care (Vademecum)
Kytril 1 mg PO/IV 30 minutes before and 12 hours after chemotherapy OTHER MEDICATIONS 1. Dexamethasone 4 mg PO BID for 6 doses after paclitaxel (for myalgias) 2. 5 Docetaxel Docetaxel 100 mg/M2 IV (over 1 h) day 1 REF: Kudelka et al. Anticancer Drugs 1996; 7:398-401 PREMEDICATIONS 1. Dexamethasone 20 mg IV 30 minutes before chemotherapy 2. Cimetidine 300 mg IV 30 minutes before chemotherapy 3. Diphenhydramine 25-50 mg IV 30 minutes before chemotherapy OTHER MEDICATIONS 1. Dexamethasone 8 mg PO BID for 8 doses—start day prior to chemotherapy (decreases lower extremity edema) Repeat every 21 days Irinotecan Irinotecan 125 mg/M2 IV (over 90 min) days 1,8, 15,22 REF: Look et al.
5 Chemotherapy Regimens Endocrine Cancer CF cisplatin/ fluorouracil (5-FU) Cisplatin 5-FU 100 mg/M2 1000 mg/M2/d IV day 1 CIV X 5 days days 1-5 REF: Kies et al. Cancer 1987; 60:2156-2160 –there are multiple variations of this regimen Gastrointestinal Genitourinary Gynecologic Head and Neck Hematologic Cancer Cancer Cancer Cancer Malignancies PREMEDICATIONS 1. Kytril 1 mg 30 minutes before and 12 hours after chemotherapy on day 1 2. Dexamethasone 20 mg IV 30 minutes before chemotherapy on day 1 OTHER MEDICATIONS 1.
Gynecol Oncol 1991; 40:264-267 PREMEDICATIONS 1. Kytril 1 mg PO/IV 30 minutes before and 12 hours after chemotherapy 2. 0 CP carboplatin/ paclitaxel Paclitaxel followed by Carboplatin 175 mg/M2 IV (over 3 h) day 1 AUC 5 IV (over 1 h) day 1 REF: Price et al. Semin Oncol 1997; 24(5suppl15):S78-S82 PREMEDICATIONS 1. Dexamethasone 20 mg IV 30 minutes before chemotherapy OR Dexamethasone 20 mg PO 6 and 12 hours prior to chemotherapy 2. Diphenhydramine 50 mg IV 30 minutes before chemotherapy 3. Cimetidine 300 mg IV 30 minutes before chemotherapy 4.