By Sudha R. Kini MD
Cytopathology of Neuroendocrine Neoplasia: Color Atlas and Text
The neuroendocrine process is interesting. it's an fascinating, complicated approach. for hundreds of years, it has sustained the curiosity of scientists, who've supplied the neighborhood with a wealth of data on neuroendocrine tumors types—history, genetics, medical presentation, surgical pathology, differential diagnoses…on every little thing except cytopathology…until now.
This special colour atlas fills a long-standing void in neuroendocrine assets. This atlas offers transparent, descriptive info at the cytopathology of neuroendocrine tumor types and differential diagnoses in a single state of the art, entire source. This distinct atlas is devoted solely to delivering specialist, illustrated insurance of the cytopathology of neuroendocrine tumors.
Inside, the content material addresses the broad distribution of the neuroendocrine cells within the physique and the ever-present nature in their neoplasms. Readers also will discover specific descriptions of the morphologic spectrum of the neoplasms (including various terminologies), in addition to their immunocytohistochemical homes, linked ultrastructural findings, secretory items, and their organization with many hereditary syndromes.
Put the ability of this atlas to paintings for you!
• specific insurance of cytomorphology of neuroendocrine neoplasia offers details no longer present in textbooks
• present tumor classifications for every physique system are integrated as an appendix on the finish of every chapter.
• Over a thousand full-color photographs detail a number tumor websites and kinds, supporting in refining the differential diagnosis.
• convenient glossary is helping make clear adjustments in terminology.
Read Online or Download Cytopathology of Neuroendocrine Neoplasia: Color Atlas and Text PDF
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Additional resources for Cytopathology of Neuroendocrine Neoplasia: Color Atlas and Text
These two images depict a malignant cell population with pleomorphic round to oblong nuclei, containing coarse, deep-staining chromatin suggesting the diagnosis of small cell carcinoma. Note scattered necrotic cells (arrows). This tumor was confirmed histologically as an atypical carcinoid. (c) 2015 Wolters Kluwer. All Rights Reserved. Chapter 3: Pulmonary Neuroendocrine Tumors 49 Fig. 32: Atypical Carcinoid. Bronchial brushings showing a syncytial tissue fragment of small to medium-sized round cells with poorly defined cell borders, indistinct cytoplasm, and large nuclei with high N/C ratios.
34 Section I: Epithelial Type Neuroendocrine Tumors A B Fig. 5: Typical Carcinoid Tumor. A, B: Direct smears of the bronchial brushings. The neoplastic cells are small to medium-sized forming broad trabeculae. Their nuclei exhibit salt–pepper chromatin, very typical of neuroendocrine neoplasms. B A C Fig. 6: Typical Carcinoid Tumor. Direct smears of the bronchial brushings. A, B: The smears demonstrate tissue fragments of medium-sized malignant cells with nuclei containing fine granular chromatin and prominent nucleoli.
The neoplastic cells are small round, resembling lymphoid cells with high N/C ratios. Note the densely stained chromatin. Note the perivascular location of the neoplastic cells. (c) 2015 Wolters Kluwer. All Rights Reserved. 34 Section I: Epithelial Type Neuroendocrine Tumors A B Fig. 5: Typical Carcinoid Tumor. A, B: Direct smears of the bronchial brushings. The neoplastic cells are small to medium-sized forming broad trabeculae. Their nuclei exhibit salt–pepper chromatin, very typical of neuroendocrine neoplasms.