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Extra resources for Evernote For Dummies (2nd Edition)
From Figure 2 it can be clearly seen that despite the extensive search for sufficient weighting factors and target dose, the F IV optimization has still lower target doses than the CCMTD optimization. 5-Gy vs. 9-Gy) but in terms of 16 XIII. 5-Gy vs. 8-Gy). selection of relative weighting factors and dose levels for different structures and volumes. B F... 2 240 0 gantry angle 10 Bladder 10 20 lO 40 50 60 Figure 2: Dose-volume histograms for the two optimized dose plans. From Figure 3 it can be seen that the level of complexity in the intensity modulation is about the same for both cases.
References  A. Niemierko, "Reporting and analyzing dose distributions: A concept of equivalent uniform dose," Medical Physics 24 (1),103-110 (1997).  A. Niemierko, "A generalized concept of Equivalent Uniform Dose (EUD) (Abstract)," Medical Physics 26 (6), 1100 (1999).  C. , "Fitting of Normal Tissue Tolerance Data to an Analytic Function," International Journal of Radiation Oncology, Biology and Physics 21 (123-135) (1991).  B. , "Tolerance of Normal Tissue to Therapeutic Radiation," International Journal of Radiation Oncology, Biology and Physics 21,109-122 (1991).
Conclusion The CCMTD formulation of' the radiotherapy optimization problem presented in this work is well suited for clinically relevant optimization. The problem formulation is entirely concerned with clinical considerations in terms of tolerance doses and volumes, and involves no iterative search for computationally sufficient optimization conditions, such as 20 lO 40 60 Figure 3: Intensity modulation for the two optimized dose plans, arbitrary length and modulation units. The method is suitable for implementation in a clinical treatment planning system, since it does not rely on linearity in the dose calculation.